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Pradip Sinha
PhD (Banaras Hindu University)
Professor, Department of Biological Sciences & Bioengineering (BSBE)
Research Interest
Goals of my researches are to identify fundamental genetic mechanisms of carcinogenesis in the fruit fly, Drosophila. Our eventual aims are also to extend these insights to explain developmental genetic basis of carcinogenesis in higher organisms including human and exploit the sophisticated genetics of Drosophila to screen for anti-cancer drug.
Education
PhD, Banaras Hindu University, Varanasi (1982)
M.Sc, Banaras Hindu University, Varanasi (1977)
B.Sc, Guwahati University (1975)
Selected Publications
Khan, S. J., Bajpai, A., Alam, M.D., Gupta, R. P., Harsh, S., Pandey, R., Goel-Bhattacharya, S., Nigam, A., Mishra, A. and Sinha, P. (2013) Epithelial neoplasia in Drosophila entails switch to primitive cell states. Proceedings of National Academy of Sciences (USA) 110(24): E2163-E2172
Jaiswal, M.; Agrawal, N. and Sinha P. (2006). Fat and Wingless signaling oppositely regulate epithelial cell-cell adhesion and distal wing development in Drosophila. Development 133, 925-935.
Shashidhara, L.S.; Agrawal, N.; Bajpai, R. Bharathi, V. and Sinha P. (1999). Negative regulation of dorso-ventral signallings by the homeotic gene Ultrabithorax during haltere development in Drosophila. Developmental Biology 212: 491-502.
Agrawal, N., Kango, M., Mishra, A. and Sinha, P. (1995). Neoplastic transformation and aberrant cell- cell interactions in genetic mosaics of lethal(2) giant larvae (lgl), a tumor suppressor gene of Drosophila. Developmental Biology 172: 218-228.
Agrawal, N., Joshi, S., Saha,D., Mishra, A., Kango, M. & Sinha, P.(1995). Epithelial hyperplasia of imaginal discs induced by mutations in Drosophila tumor suppressor genes: growth and pattern formation in genetics mosaics. Developmental Biology 169: 387-398.
Awards & Fellowships
Satish Chandra Agrawal Chair Professor at IITK , 2009 –11